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Antimicrobial Agents and Chemotherapy, March 2007, p. 1107-1108, Vol. 51, No. 3
0066-4804/07/$08.00+0     doi:10.1128/AAC.01320-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Can Alcohol-Based Hand-Rub Solutions Cause You To Lose Your Driver's License? Comparative Cutaneous Absorption of Various Alcohols{triangledown}

T. L. Brown,1 S. Gamon,2 P. Tester,3 R. Martin,2 K. Hosking,2 G. C. Bowkett,3 D. Gerostamoulos,4 and M. L. Grayson1,5,6*

Infectious Disease,1 Infection Control Departments, Austin Health,2 Victoria Police,3 Victorian Institute of Forensic Medicine, Melbourne,4 Department of Epidemiology and Preventive Medicine, Monash University, Melbourne,5 Department of Medicine, University of Melbourne, Melbourne, Victoria 3084, Australia6

Received 23 October 2006/ Returned for modification 22 November 2006/ Accepted 17 December 2006

We assessed cutaneous ethanol (ETOH) and isopropanol (ISOP) absorption after intensive (30 times per h) use of alcohol-based hand-rub solutions by healthcare workers (HCWs). ETOH was detectable in the breath of 6/20 HCWs (0.001 to 0.0025%) at 1 to 2 min postexposure and in the serum of 2/20 HCWs at 5 to 7 min postexposure. Serum ISOP levels were unrecordable at all time points.

* Corresponding author. Mailing address: Infectious Diseases Department, Austin Health, Studley Rd., Heidelberg, VIC 3084, Australia. Phone: 613 9496 6676. Fax: 613 9496 6677. E-mail: Lindsay.Grayson{at}austin.org.au.

{triangledown} Published ahead of print on 28 December 2006.

Antimicrobial Agents and Chemotherapy, March 2007, p. 1107-1108, Vol. 51, No. 3
0066-4804/07/$08.00+0     doi:10.1128/AAC.01320-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.





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